S100G

Across TCGA pan-cancer cohorts, S100G RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of S100G’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where S100G RNA is more highly expressed in tumor relative to normal tissue. In most cancer types S100G is over-expressed in tumor, although a few such as STAD show the opposite, repressed pattern.

KIRC, ESCA, and STAD are the cancer types where S100G tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in S100G RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.319	.006	5	view →
ESCA	All	II,III,IV	+1.020	.005	4	view →
STAD	Male	All	−1.873	.014	2	view →
UCEC	All	All	+0.767	.036	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

S100G–KIRC

Open the KIRC breakdown →