S100G

Across TCGA patient cohorts, S100G mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible S100G-associated genes across cancer lineages are p62 Lck ligand and 4E-BP1. Each is linked with S100G in more than 1 cancer types. Because this analysis shows association rather than direction, both S100G-to-partner and partner-to-S100G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p62 Lck ligand grouped by S100G-low versus S100G-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S100G→partner) and Y-score (partner→S100G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p62 Lck ligand →	+0.595	+2.817	.002	.036	3	1
UCEC	4E-BP1 →	+0.557	+2.837	<.001	.035	2	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

p62 Lck ligand by S100G expression — UCEC

Explore this box plot interactively →