Across TCGA patient cohorts, S100A7A RNA expression is significantly associated with the go_rna of many other GO terms, with 6,402 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible S100A7A-associated GO terms across cancer lineages are Autocrine signaling, Protein nitrosylation, and Regulation of integrin biosynthetic process. Each is linked with S100A7A in more than 11 cancer types. Because this analysis shows association rather than direction, both S100A7A-to-partner and partner-to-S100A7A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (S100A7A→partner) and Y-score (partner→S100A7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Autocrine signaling →	+0.133	+2.535	<.001	<.001	3	12
ESCA	Protein nitrosylation →	+0.052	+2.013	<.001	<.001	3	11
ESCA	Regulation of integrin biosynthetic process →	+0.143	+2.172	<.001	<.001	3	11
ESCA	Defense response to fungus →	+0.084	+3.025	<.001	<.001	3	10
ESCA	Antimicrobial humoral immune response mediated by antimicrobial peptide →	+0.075	+1.701	<.001	<.001	3	10
ESCA	Leukocyte aggregation →	+0.067	+1.853	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,402 associations by consensus.

Exploration

S100A7A survival (RNA) · tumor vs normal (RNA) · all S100A7A data types