Across TCGA patient cohorts, S100A7A protein abundance is significantly associated with the RNA expression of many other genes, with 6,247 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible S100A7A-associated genes across cancer lineages are AKR1B15, MTERF2, and PI3. Each is linked with S100A7A in more than 2 cancer types. Because this analysis shows association rather than direction, both S100A7A-to-partner and partner-to-S100A7A results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S100A7A→partner) and Y-score (partner→S100A7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AKR1B15 →	+1.612	+3.747	.001	.002	3	3
BRCA	MTERF2 →	-0.521	-1.294	<.001	.008	3	3
LSCC	PI3 →	+2.615	+1.684	<.001	<.001	3	3
LSCC	S100A8 →	+2.895	+2.294	<.001	<.001	3	3
LSCC	S100A7 →	+4.160	+2.595	<.001	<.001	3	3
LSCC	LCN2 →	+1.969	+1.312	<.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,247 associations by consensus.

Exploration

S100A7A survival (RNA) · tumor vs normal (RNA) · all S100A7A data types