Across TCGA patient cohorts, S100A7A mutation is significantly associated with the RNA expression of many other genes, with 182 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible S100A7A-associated genes across cancer lineages are ACKR3, RSAD1, and MIR511. Each is linked with S100A7A in more than 1 cancer types. Because this analysis shows association rather than direction, both S100A7A-to-partner and partner-to-S100A7A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S100A7A→partner) and Y-score (partner→S100A7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACKR3 →	-1.149	-3.584	<.001	.003	3	2
SKCM	RSAD1 →	+0.539	+3.341	.002	.005	3	2
SKCM	MIR511 →	+0.129	+4.315	<.001	.005	3	2
SKCM	IDI2-AS1 →	+1.283	+3.341	.001	.005	3	2
UCEC	RNA5SP411 →	+1.019	+2.171	.002	.009	3	1
HNSC	TRIM53BP →	+0.250	+4.505	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 182 associations by consensus.

Exploration

S100A7A survival (RNA) · tumor vs normal (RNA) · all S100A7A data types