Across TCGA patient cohorts, S100A7A mutation is significantly associated with the immune_cell of many other genes, with 6 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible S100A7A-associated genes across cancer lineages are CMP, Neurons, and Platelets. Each is linked with S100A7A in more than 1 cancer types. Because this analysis shows association rather than direction, both S100A7A-to-partner and partner-to-S100A7A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S100A7A→partner) and Y-score (partner→S100A7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CMP →	+0.038	+2.074	.017	.033	3	2
SKCM	Neurons →	+0.026	+2.189	.007	.035	3	2
SKCM	Platelets →	+0.015	+1.769	.022	.044	3	2
LIHC	Chondrocytes →	+0.012	+6.914	<.001	.016	3	2
LIHC	Monocytes →	+0.014	+5.305	.007	.048	3	1
SKCM	Endothelial cells →	-0.051	-3.315	.011	.010	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

S100A7A survival (RNA) · tumor vs normal (RNA) · all S100A7A data types