S100A7

Across TCGA patient cohorts, S100A7 protein abundance is significantly associated with the RNA expression of many other genes, with 9,993 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible S100A7-associated genes across cancer lineages are S100A8, S100A9, and PI3. Each is linked with S100A7 in more than 5 cancer types. Because this analysis shows association rather than direction, both S100A7-to-partner and partner-to-S100A7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, S100A7 versus S100A8 in BRCA, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S100A7→partner) and Y-score (partner→S100A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	S100A8 →	+2.784	+2.045	<.001	<.001	3	6
LUAD	S100A9 →	+3.457	+2.649	<.001	<.001	3	6
UCEC	PI3 →	+2.354	+1.923	<.001	<.001	3	5
HNSC	IVL →	+1.968	+1.092	<.001	<.001	3	5
HNSC	S100A7A →	+2.827	+1.917	<.001	<.001	3	5
LUAD	RHOV →	+2.542	+1.817	<.001	.005	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,993 associations by consensus.

S100A7 vs S100A8 — BRCA

Explore this scatter interactively →