S100A12

Across TCGA patient cohorts, S100A12 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,218 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible S100A12-associated proteins across cancer lineages are S100A8, S100A9, and MPO. Each is linked with S100A12 in more than 9 cancer types. Because this analysis shows association rather than direction, both S100A12-to-partner and partner-to-S100A12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, S100A12 versus S100A8 in PDAC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (S100A12→partner) and Y-score (partner→S100A12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	S100A8 →	+1.661	+0.981	<.001	<.001	3	10
PDAC	S100A9 →	+1.486	+0.869	<.001	.001	3	10
GBM	MPO →	+1.160	+1.291	<.001	<.001	3	10
GBM	PADI4 →	+1.288	+1.420	<.001	<.001	3	10
PDAC	CAMP →	+1.626	+0.941	<.001	<.001	3	10
GBM	MMP9 →	+1.354	+1.444	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,218 associations by consensus.

S100A12 vs S100A8 — PDAC

Explore this scatter interactively →