S100A12

Across TCGA patient cohorts, S100A12 protein abundance is significantly associated with the RNA expression of many other genes, with 17,868 significant associations in total. GBM shows the largest number of these associations.

The most reproducible S100A12-associated genes across cancer lineages are S100A8, FCGR3B, and CXCL1. Each is linked with S100A12 in more than 9 cancer types. Because this analysis shows association rather than direction, both S100A12-to-partner and partner-to-S100A12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, S100A12 versus S100A8 in LSCC, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S100A12→partner) and Y-score (partner→S100A12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	S100A8 →	+2.355	+1.466	<.001	<.001	3	10
PDAC	FCGR3B →	+1.939	+1.774	<.001	<.001	3	10
LSCC	CXCL1 →	+2.122	+1.344	<.001	<.001	3	10
LUAD	CXCL8 →	+2.601	+1.684	<.001	<.001	3	10
LSCC	CEACAM3 →	+0.935	+1.718	<.001	<.001	3	10
GBM	FPR2 →	+1.361	+1.732	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,868 associations by consensus.

S100A12 vs S100A8 — LSCC

Explore this scatter interactively →