S100A12

Across TCGA patient cohorts, S100A12 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible S100A12-associated genes across cancer lineages are Smooth muscle, Adipocytes, and HSC. Each is linked with S100A12 in more than 1 cancer types. Because this analysis shows association rather than direction, both S100A12-to-partner and partner-to-S100A12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Smooth muscle grouped by S100A12-low versus S100A12-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S100A12→partner) and Y-score (partner→S100A12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Smooth muscle →	+0.098	+1.591	.040	.044	3	1
UCEC	Adipocytes →	+0.047	+3.729	<.001	.002	3	1
SKCM	HSC →	-0.090	-2.775	.011	.003	2	1
UCEC	Hepatocytes →	+0.021	+2.828	.001	.036	1	2
UCEC	pDC →	+0.084	+2.818	.004	.037	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Smooth muscle by S100A12 expression — SKCM

Explore this box plot interactively →