S100A11

Across TCGA patient cohorts, S100A11 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible S100A11-associated genes across cancer lineages are RNU6-590P, RPEP5, and OR4C49P. Each is linked with S100A11 in more than 1 cancer types. Because this analysis shows association rather than direction, both S100A11-to-partner and partner-to-S100A11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-590P grouped by S100A11-low versus S100A11-high in THCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S100A11→partner) and Y-score (partner→S100A11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	RNU6-590P →	+0.273	+7.962	<.001	.007	3	1
THCA	RPEP5 →	+0.074	+7.962	<.001	.007	3	1
THCA	OR4C49P →	+0.024	+7.962	<.001	.007	3	1
UCEC	RPL22P14 →	+0.298	+5.109	<.001	.001	3	1
UCEC	RNU6-1077P →	+0.721	+4.188	.001	.009	3	1
UCEC	RPSAP60 →	+0.140	+4.302	.002	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

RNU6-590P by S100A11 expression — THCA

Explore this box plot interactively →