Q-omics provides the consensus-scored RPSAP60 profile across patient tissues and cancer cell-line models. RPSAP60 expression is associated with patient survival in 10 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, RPSAP60 is differentially expressed in 4, with the highest sampling consensus in COAD. Additionally, RPSAP60 RNA expression shows 6,391 significant protein co-abundance associations, with the highest sampling consensus in LSCC. Together, these results highlight ACC, COAD, and LSCC as cancer lineages where RPSAP60 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RPSAP60 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RPSAP60 survival associations across molecular data types. RPSAP60 RNA expression shows survival associations in the most cancer types (10). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RPSAP60 RNA expression–survival associations across cancer types. High RPSAP60 expression shows unfavorable associations in ACC, UVM, OV and PCPG, but favorable associations in UCS and READ. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .004). Together, the overview and detailed table identify ACC as the clearest survival context for RPSAP60 RNA expression.
This table summarizes RPSAP60 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for RPSAP60. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RPSAP60 shows higher tumor expression in COAD, HNSC, LUSC and BLCA. The COAD box plot shows higher RPSAP60 RNA expression in tumor versus normal tissue (log2 FC = +0.083, t-test p = .004).
This table shows molecular features associated with RPSAP60 in patient tissues and cancer cell lines. In patient samples, RPSAP60 shows the broadest associations at the RNA and protein expression levels, with LSCC recurring as the lineage with the largest associated feature set.
