S100A1

Across TCGA cell cohorts, S100A1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible S100A1-associated genes across cancer lineages are DRD3, FCN2, and CCER1. Each is linked with S100A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both S100A1-to-partner and partner-to-S100A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DRD3 grouped by S100A1-low versus S100A1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (S100A1→partner) and Y-score (partner→S100A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	DRD3 →	+0.012	+4.977	<.001	.007	3	1
LARGE_INTESTINE	FCN2 →	+0.052	+5.415	<.001	.004	3	1
LARGE_INTESTINE	CCER1 →	+0.012	+4.977	<.001	.007	3	1
LARGE_INTESTINE	BTNL2 →	+0.109	+5.415	<.001	.004	3	1
LARGE_INTESTINE	CD300H →	+0.052	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

DRD3 by S100A1 expression — LARGE_INTESTINE

Explore this box plot interactively →