RUVBL1-AS1

Across TCGA pan-cancer cohorts, RUVBL1-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated RUVBL1-AS1 data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher RUVBL1-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated RUVBL1-AS1 expression acts as an unfavorable survival marker, although some lineages such as READ and CHOL show a favorable association.

READ, BLCA, and THCA are the cancer types where RUVBL1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Median	II,III,IV	0.930	0.720	.004	52	view →
BLCA	OS	Quartile	III,IV	0.414	0.621	.007	47	view →
THCA	DFS	Tertile	II,III,IV	0.622	0.869	.002	45	view →
UCEC	DFS	Tertile	All	0.849	0.915	.005	34	view →
CESC	DFS	Median	All	0.403	0.716	.001	22	view →
CHOL	DFS	Median	All	0.649	0.299	.004	21	view →
DLBC	DFS	Tertile	All	0.281	0.835	.007	21	view →
LIHC	DFS	Tertile	All	0.438	0.575	.005	19	view →
LUSC	DFS	Median	IV	0.134	0.827	.014	18	view →
UCS	DFS	Tertile	IV	0.996	0.522	.015	18	view →
TGCT	DFS	Tertile	II,III,IV	0.724	1.000	.037	14	view →
LUAD	DFS	Tertile	IV	0.454	1.000	.042	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

RUVBL1-AS1–READ (OS)

Open the READ breakdown →