RUNDC3B

Across TCGA patient cohorts, RUNDC3B mutation is significantly associated with the RNA expression of many other genes, with 4,633 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RUNDC3B-associated genes across cancer lineages are SNORD82, SLC7A11, and OR9G4. Each is linked with RUNDC3B in more than 2 cancer types. Because this analysis shows association rather than direction, both RUNDC3B-to-partner and partner-to-RUNDC3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD82 grouped by RUNDC3B-low versus RUNDC3B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RUNDC3B→partner) and Y-score (partner→RUNDC3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNORD82 →	+0.442	+1.717	<.001	.001	3	3
UCEC	SLC7A11 →	+0.778	+2.513	<.001	<.001	3	3
SCLC	OR9G4 →	+0.073	+5.624	<.001	.003	3	2
SKCM	RUNDC3A →	-0.657	-3.565	.006	.002	3	2
UCEC	KRBA2 →	+0.264	+2.136	<.001	<.001	3	2
UCEC	MCMBP →	+0.522	+2.486	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,633 associations by consensus.

SNORD82 by RUNDC3B expression — UCEC

Explore this box plot interactively →