RTRAF

Across TCGA patient cohorts, RTRAF mutation is significantly associated with the RNA expression of many other genes, with 3,136 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RTRAF-associated genes across cancer lineages are RNA5SP412, RNU6-794P, and RN7SL248P. Each is linked with RTRAF in more than 2 cancer types. Because this analysis shows association rather than direction, both RTRAF-to-partner and partner-to-RTRAF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP412 grouped by RTRAF-low versus RTRAF-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RTRAF→partner) and Y-score (partner→RTRAF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP412 →	+0.476	+2.137	<.001	<.001	3	3
CESC	RNU6-794P →	+0.438	+5.144	<.001	.003	3	2
UCEC	RN7SL248P →	+0.048	+2.847	<.001	.008	3	2
UCEC	RNA5SP411 →	+1.318	+2.045	<.001	<.001	3	2
COAD	USP12PY →	+0.135	+4.717	<.001	.003	3	2
COAD	ELAVL4-AS1 →	+0.143	+4.602	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,136 associations by consensus.

RNA5SP412 by RTRAF expression — UCEC

Explore this box plot interactively →