RTN4R

Across TCGA patient cohorts, RTN4R mutation is significantly associated with the RNA expression of many other genes, with 87 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible RTN4R-associated genes across cancer lineages are MTND4P30, MIR4734, and RNU1-17P. Each is linked with RTN4R in more than 1 cancer types. Because this analysis shows association rather than direction, both RTN4R-to-partner and partner-to-RTN4R results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND4P30 grouped by RTN4R-low versus RTN4R-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RTN4R→partner) and Y-score (partner→RTN4R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MTND4P30 →	+0.069	+4.178	.007	.009	3	2
SKCM	MIR4734 →	+0.336	+3.533	.002	.007	3	2
UCEC	RNU1-17P →	+0.403	+3.613	<.001	.001	3	2
UCEC	OR2E1P →	+0.142	+4.027	<.001	.001	3	2
UCEC	RNU6-638P →	+0.666	+3.337	.008	.001	3	2
UCEC	RNU6-1213P →	+0.261	+4.069	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 87 associations by consensus.

MTND4P30 by RTN4R expression — BLCA

Explore this box plot interactively →