Q-omics provides the consensus-scored MIR4734 profile across patient tissues and cancer cell-line models. MIR4734 expression is associated with patient survival in 8 of 34 cancer types, with the highest sampling consensus in THYM. Among the 18 cancer types available for tumor–normal comparison, MIR4734 is differentially expressed in 6, with the highest sampling consensus in KICH. Additionally, MIR4734 RNA expression shows 3,016 significant protein co-abundance associations, with the highest sampling consensus in CCRCC. Together, these results highlight THYM, KICH, and CCRCC as cancer lineages where MIR4734 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR4734 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR4734 survival associations across molecular data types. MIR4734 RNA expression shows survival associations in the most cancer types (8). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR4734 RNA expression–survival associations across cancer types. High MIR4734 expression shows unfavorable associations in THYM, THCA and TGCT, but favorable associations in HNSC, SKCM and CESC. The THYM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify THYM as the clearest survival context for MIR4734 RNA expression.
This table summarizes MIR4734 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 6. The strongest signals are observed in KICH for RNA.
This table ranks reproducible tumor–normal expression differences for MIR4734. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR4734 shows lower tumor expression in KICH, KIRC, ESCA and THCA and higher tumor expression in BLCA and LIHC. The KICH box plot shows higher MIR4734 RNA expression in normal versus tumor tissue (log2 FC = −0.652, t-test p = .004).
This table shows molecular features associated with MIR4734 in patient tissues and cancer cell lines. In patient samples, MIR4734 shows the broadest associations at the RNA and protein expression levels, with CCRCC recurring as the lineage with the largest associated feature set.
