MIR4734

Across TCGA patient cohorts, MIR4734 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,616 significant associations in total. LIHC shows the largest number of these associations.

The most reproducible MIR4734-associated GO terms across cancer lineages are Protein import into peroxisome matrix, substrate release, DNA replication, and Protein insertion into ER membrane by stop-transfer membrane-anchor sequence. Each is linked with MIR4734 in more than 4 cancer types. Because this analysis shows association rather than direction, both MIR4734-to-partner and partner-to-MIR4734 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein import into peroxisome matrix, substrate release grouped by MIR4734-low versus MIR4734-high in LIHC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4734→partner) and Y-score (partner→MIR4734) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	Protein import into peroxisome matrix, substrate release →	+0.041	+0.131	<.001	<.001	3	5
BLCA	DNA replication →	+0.018	+0.118	<.001	.001	3	5
BLCA	Protein insertion into ER membrane by stop-transfer membrane-anchor sequence →	+0.023	+0.191	<.001	<.001	2	5
BLCA	Mitochondrial DNA replication →	+0.023	+0.176	<.001	<.001	3	4
OV	Positive regulation of protein modification by small protein conjugation or removal →	+0.015	+0.309	<.001	<.001	3	3
UCEC	Regulation of complement-dependent cytotoxicity →	-0.055	-0.122	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,616 associations by consensus.

Protein import into peroxisome matrix, substrate release by MIR4734 expression — LIHC

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