RTN2

Across TCGA patient cohorts, RTN2 mutation is significantly associated with the RNA expression of many other genes, with 911 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RTN2-associated genes across cancer lineages are MIR4675, SNRPGP17, and RNU1-36P. Each is linked with RTN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RTN2-to-partner and partner-to-RTN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4675 grouped by RTN2-low versus RTN2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RTN2→partner) and Y-score (partner→RTN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR4675 →	+0.269	+4.837	<.001	.003	3	2
CESC	SNRPGP17 →	+0.385	+3.874	<.001	.004	3	2
READ	RNU1-36P →	+0.227	+4.421	.001	.009	3	2
READ	TRAJ14 →	+0.569	+4.925	<.001	.004	3	2
READ	UBE2V1P13 →	+0.196	+5.054	<.001	.001	3	2
BRCA	RNU7-8P →	+0.848	+4.844	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 911 associations by consensus.

MIR4675 by RTN2 expression — CESC

Explore this box plot interactively →