RTL5

Across TCGA patient cohorts, RTL5 mutation is significantly associated with the RNA expression of many other genes, with 4,243 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RTL5-associated genes across cancer lineages are RN7SL248P, MTND5P35, and ATP6V1G1P7. Each is linked with RTL5 in more than 2 cancer types. Because this analysis shows association rather than direction, both RTL5-to-partner and partner-to-RTL5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by RTL5-low versus RTL5-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RTL5→partner) and Y-score (partner→RTL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RN7SL248P →	+0.049	+3.973	<.001	.008	3	3
CESC	MTND5P35 →	+0.028	+5.539	<.001	.004	3	3
LGG	ATP6V1G1P7 →	+0.124	+7.977	<.001	.007	3	2
LUSC	MIR769 →	+0.253	+3.446	<.001	.009	3	2
LUSC	MIR4265 →	+0.346	+4.038	<.001	.003	3	2
UCEC	CCL5 →	+0.764	+3.000	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,243 associations by consensus.

RN7SL248P by RTL5 expression — COAD

Explore this box plot interactively →