RTEL1-TNFRSF6B

Across TCGA patient cohorts, RTEL1-TNFRSF6B protein abundance is significantly associated with the RNA expression of many other genes, with 11,482 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible RTEL1-TNFRSF6B-associated genes across cancer lineages are COL17A1, SEMA3C, and CAV2. Each is linked with RTEL1-TNFRSF6B in more than 6 cancer types. Because this analysis shows association rather than direction, both RTEL1-TNFRSF6B-to-partner and partner-to-RTEL1-TNFRSF6B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RTEL1-TNFRSF6B versus COL17A1 in LSCC, with a Pearson correlation of 0.92.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RTEL1-TNFRSF6B→partner) and Y-score (partner→RTEL1-TNFRSF6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	COL17A1 →	+2.874	+1.723	<.001	<.001	3	7
UCEC	SEMA3C →	+1.874	+2.134	<.001	<.001	3	6
BRCA	CAV2 →	+1.196	+1.558	<.001	<.001	3	5
LUAD	EREG →	+2.040	+1.129	<.001	<.001	3	5
UCEC	GJB2 →	+2.553	+2.090	.001	<.001	3	5
UCEC	SPRR1B →	+3.506	+1.946	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,482 associations by consensus.

RTEL1-TNFRSF6B vs COL17A1 — LSCC

Explore this scatter interactively →