RSRC2

Across TCGA patient cohorts, RSRC2 mutation is significantly associated with the RNA expression of many other genes, with 1,846 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RSRC2-associated genes across cancer lineages are RNU1-17P, RNA5SP369, and RN7SL248P. Each is linked with RSRC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RSRC2-to-partner and partner-to-RSRC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-17P grouped by RSRC2-low versus RSRC2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSRC2→partner) and Y-score (partner→RSRC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU1-17P →	+0.459	+5.103	<.001	.008	3	2
UCEC	RNA5SP369 →	+0.385	+2.276	<.001	<.001	3	2
UCEC	RN7SL248P →	+0.044	+2.783	<.001	.009	3	2
UCEC	IGHD4-4 →	+0.593	+3.155	<.001	<.001	3	2
UCEC	BNIP3P41 →	+0.012	+4.539	<.001	<.001	3	2
SKCM	MLLT10P2 →	+0.171	+5.469	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,846 associations by consensus.

RNU1-17P by RSRC2 expression — CESC

Explore this box plot interactively →