RSPH9

Across TCGA patient cohorts, RSPH9 mutation is significantly associated with the RNA expression of many other genes, with 1,194 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RSPH9-associated genes across cancer lineages are SNORD116-15, PGBD4P2, and TMEM225. Each is linked with RSPH9 in more than 1 cancer types. Because this analysis shows association rather than direction, both RSPH9-to-partner and partner-to-RSPH9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD116-15 grouped by RSPH9-low versus RSPH9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSPH9→partner) and Y-score (partner→RSPH9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNORD116-15 →	+0.312	+2.384	.003	.002	3	2
READ	PGBD4P2 →	+0.162	+6.257	<.001	.001	3	1
READ	TMEM225 →	+0.114	+5.039	<.001	.008	3	1
READ	RNU6-1274P →	+0.547	+5.925	<.001	.002	3	1
READ	FOXO1B →	+0.146	+5.039	<.001	.008	3	1
READ	OR6K5P →	+0.057	+6.257	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,194 associations by consensus.

SNORD116-15 by RSPH9 expression — UCEC

Explore this box plot interactively →