RSPH9

Across TCGA cell cohorts, RSPH9 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,554 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RSPH9-associated GO terms across cancer lineages are Regulation of DNA-templated transcription initiation, Positive regulation of intracellular steroid hormone receptor signaling pathway, and Regulation of mRNA processing. Each is linked with RSPH9 in more than 8 cancer types. Because this analysis shows association rather than direction, both RSPH9-to-partner and partner-to-RSPH9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA-templated transcription initiation grouped by RSPH9-low versus RSPH9-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RSPH9→partner) and Y-score (partner→RSPH9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of DNA-templated transcription initiation →	+0.050	+0.181	.002	.008	3	9
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.158	+0.130	<.001	.002	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of mRNA processing →	+0.087	+0.149	<.001	<.001	3	9
BLOOD_Myeloma	Spliceosomal tri-snRNP complex assembly →	+0.088	+0.293	<.001	.004	3	9
UPPER_AERODIGESTIVE_TRACT	Transcription initiation at RNA polymerase II promoter →	+0.065	+0.148	<.001	<.001	3	9
BLOOD_Lymphoma	Negative regulation of gene expression, epigenetic →	+0.050	+0.214	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,554 associations by consensus.

Regulation of DNA-templated transcription initiation by RSPH9 expression — LARGE_INTESTINE

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