RSPH9

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RSPH9 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RSPH9-associated genes across cancer lineages are KRTAP5-3 and MAGEB4. Each is linked with RSPH9 in more than 1 cancer types. Because this analysis shows association rather than direction, both RSPH9-to-partner and partner-to-RSPH9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP5-3 grouped by RSPH9-low versus RSPH9-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSPH9→partner) and Y-score (partner→RSPH9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaKRTAP5-3 →+0.024+4.922<.001.00931
LARGE_INTESTINEMAGEB4 →+0.012+5.415.009.00431
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

KRTAP5-3 by RSPH9 expression — BLOOD_Leukemia

Box plot of KRTAP5-3 in RSPH9-low vs RSPH9-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration