RSPH14

Across TCGA patient cohorts, RSPH14 mutation is significantly associated with the RNA expression of many other genes, with 1,745 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RSPH14-associated genes across cancer lineages are RNU6-391P, TRAJ9, and RNA5SP411. Each is linked with RSPH14 in more than 2 cancer types. Because this analysis shows association rather than direction, both RSPH14-to-partner and partner-to-RSPH14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-391P grouped by RSPH14-low versus RSPH14-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSPH14→partner) and Y-score (partner→RSPH14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-391P →	+0.201	+3.027	<.001	.001	3	3
UCEC	TRAJ9 →	+0.657	+2.006	<.001	.002	3	3
UCEC	RNA5SP411 →	+0.867	+1.808	.001	.007	3	2
BRCA	KRT18P12 →	+0.095	+4.220	<.001	.009	3	2
BRCA	RNA5SP113 →	+0.308	+5.711	<.001	.001	3	2
BRCA	RPL38P1 →	+0.303	+5.396	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,745 associations by consensus.

RNU6-391P by RSPH14 expression — UCEC

Explore this box plot interactively →