RSBN1

Across TCGA patient cohorts, RSBN1 mutation is significantly associated with the RNA expression of many other genes, with 4,484 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RSBN1-associated genes across cancer lineages are APBA3, MIR629, and RAC3. Each is linked with RSBN1 in more than 2 cancer types. Because this analysis shows association rather than direction, both RSBN1-to-partner and partner-to-RSBN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, APBA3 grouped by RSBN1-low versus RSBN1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSBN1→partner) and Y-score (partner→RSBN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	APBA3 →	+0.359	+3.301	<.001	<.001	3	3
LUAD	MIR629 →	+0.349	+4.099	<.001	.002	3	3
UCEC	RAC3 →	+0.530	+1.847	.007	.007	3	3
UCEC	NCKIPSD →	+0.408	+1.917	<.001	<.001	3	3
UCEC	LINC00461 →	+0.576	+1.316	.002	.006	3	3
UCEC	RBM15B →	+0.362	+3.021	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,484 associations by consensus.

APBA3 by RSBN1 expression — UCEC

Explore this box plot interactively →