RRS1

Across TCGA patient cohorts, RRS1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,727 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RRS1-associated genes across cancer lineages are RNASE1, CMAHP, and OLFML1. Each is linked with RRS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both RRS1-to-partner and partner-to-RRS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RRS1 versus RNASE1 in UCEC, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RRS1→partner) and Y-score (partner→RRS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNASE1 →	-1.521	-0.409	<.001	<.001	3	7
BRCA	CMAHP →	-0.795	-0.430	.003	.001	3	7
OV	OLFML1 →	-1.154	-0.368	<.001	.001	3	7
LSCC	AHCY →	+0.746	+0.440	<.001	<.001	3	6
OV	COMP →	-1.883	-0.317	<.001	<.001	3	6
OV	MGP →	-1.459	-0.435	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,727 associations by consensus.

RRS1 vs RNASE1 — UCEC

Explore this scatter interactively →