RRN3P1

Across TCGA patient cohorts, RRN3P1 mutation is significantly associated with the RNA expression of many other genes, with 50 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible RRN3P1-associated genes across cancer lineages are WBP1LP6, RNU6-4P, and IGHD3-16. Each is linked with RRN3P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RRN3P1-to-partner and partner-to-RRN3P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WBP1LP6 grouped by RRN3P1-low versus RRN3P1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RRN3P1→partner) and Y-score (partner→RRN3P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	WBP1LP6 →	+0.226	+5.540	<.001	.004	3	2
UCEC	RNU6-4P →	+0.667	+3.649	.005	.005	3	1
UCEC	IGHD3-16 →	+2.121	+3.417	<.001	.003	3	1
UCEC	IGHD3-9 →	+1.962	+4.120	.002	.001	3	1
UCEC	RN7SKP220 →	+0.438	+4.923	<.001	.002	3	1
UCEC	LINC01501 →	+0.176	+3.820	.009	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

WBP1LP6 by RRN3P1 expression — BRCA

Explore this box plot interactively →