RRN3P1

Across TCGA pan-cancer cohorts, RRN3P1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated RRN3P1 data layer compared with 2 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RRN3P1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RRN3P1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and PAAD show a favorable association.

HNSC, PAAD, and THYM are the cancer types where RRN3P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	IV	0.753	0.587	.006	58	view →
PAAD	DFS	Quartile	II,III,IV	0.568	0.316	.001	33	view →
THYM	OS	Quartile	II,III,IV	1.000	0.617	.002	27	view →
UCS	DFS	Median	II,III,IV	0.513	0.203	.002	20	view →
ACC	DFS	Tertile	II,III,IV	0.468	0.910	.007	20	view →
PRAD	DFS	Tertile	All	0.814	0.936	<.001	18	view →
READ	OS	Tertile	III,IV	0.790	0.256	.003	17	view →
KIRP	DFS	Quartile	II,III,IV	0.805	0.504	.022	15	view →
UVM	DFS	Tertile	III,IV	0.312	0.844	.012	13	view →
COAD	DFS	Tertile	All	0.320	0.648	.001	13	view →
KIRC	DFS	Median	II,III,IV	0.435	0.580	.035	12	view →
LUAD	OS	Quartile	All	0.860	0.732	.001	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

RRN3P1–HNSC (DFS)

Open the HNSC breakdown →