RRN3P1

Across TCGA pan-cancer cohorts, RRN3P1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of RRN3P1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RRN3P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RRN3P1 is over-expressed in tumor, although a few such as BLCA and KICH show the opposite, repressed pattern.

KIRC, BLCA, and KICH are the cancer types where RRN3P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RRN3P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	IV	+0.620	<.001	9	view →
BLCA	Male	III,IV	−1.021	.001	8	view →
KICH	Female	All	−1.149	<.001	7	view →
BRCA	All	III,IV	−1.081	<.001	6	view →
COAD	Female	II,III,IV	+0.735	<.001	6	view →
THCA	All	All	−0.389	.001	6	view →
STAD	All	II,III,IV	+0.576	.017	4	view →
LUSC	All	II,III,IV	−0.397	.013	4	view →
HNSC	All	All	+0.179	.015	4	view →
LUAD	All	III,IV	−0.495	.006	3	view →
READ	All	All	+0.968	<.001	2	view →
KIRP	All	All	+0.522	.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

RRN3P1–KIRC

Open the KIRC breakdown →