RRM1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RRM1 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,400 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RRM1-associated proteins across cancer lineages are RFC1_T506, POLD1, and POLD3. Each is linked with RRM1 in more than 9 cancer types. Because this analysis shows association rather than direction, both RRM1-to-partner and partner-to-RRM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RRM1 versus RFC1_T506 in LUAD, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RRM1→partner) and Y-score (partner→RRM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADRFC1_T506 →+0.959+0.445<.001<.001310
UCECPOLD1 →+0.365+0.905<.001<.00139
GBMPOLD3 →+0.477+0.549<.001<.00139
LUADRRM2 →+0.658+0.419<.001<.00139
GBMSMC2 →+0.659+0.540<.001<.00139
GBMSMC4 →+0.624+0.527<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 19,400 associations by consensus.

RRM1 vs RFC1_T506 — LUAD

Per-sample scatter of RRM1 vs RFC1_T506 in LUAD (Pearson r = 0.54).

Explore this scatter interactively →

Exploration