RRM1-AS1

Across TCGA patient cohorts, RRM1-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,384 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RRM1-AS1-associated proteins across cancer lineages are RRM1, SMC3, and MCM5. Each is linked with RRM1-AS1 in more than 4 cancer types. Because this analysis shows association rather than direction, both RRM1-AS1-to-partner and partner-to-RRM1-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RRM1-AS1 versus RRM1 in GBM, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RRM1-AS1→partner) and Y-score (partner→RRM1-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RRM1 →	+0.425	+0.574	<.001	<.001	3	5
GBM	SMC3 →	+0.282	+0.443	<.001	<.001	3	5
GBM	MCM5 →	+0.714	+0.572	.001	<.001	3	5
GBM	TPX2 →	+0.740	+0.591	<.001	<.001	3	4
GBM	POLR2B →	+0.160	+0.438	.001	.001	3	4
LSCC	NUP107 →	+0.161	+0.463	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,384 associations by consensus.

RRM1-AS1 vs RRM1 — GBM

Explore this scatter interactively →