RRAS

Across TCGA patient cohorts, RRAS protein abundance is significantly associated with the RNA expression of many other genes, with 17,362 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RRAS-associated genes across cancer lineages are JPH2, CNN1, and GFPT2. Each is linked with RRAS in more than 8 cancer types. Because this analysis shows association rather than direction, both RRAS-to-partner and partner-to-RRAS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RRAS versus JPH2 in UCEC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RRAS→partner) and Y-score (partner→RRAS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JPH2 →	+1.028	+0.384	.001	.004	3	9
COAD	CNN1 →	+1.939	+0.514	<.001	<.001	3	8
OV	GFPT2 →	+1.382	+0.440	<.001	<.001	3	7
OV	SERPING1 →	+1.535	+0.452	<.001	<.001	3	7
OV	NBL1 →	+1.011	+0.320	.001	<.001	3	7
COAD	LMOD1 →	+1.497	+0.548	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,362 associations by consensus.

RRAS vs JPH2 — UCEC

Explore this scatter interactively →