RRAS

Across TCGA cell cohorts, RRAS RNA expression is significantly associated with the RNA expression of many other genes, with 11,436 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RRAS-associated genes across cancer lineages are CAVIN1, OPTN, and FAM214B. Each is linked with RRAS in more than 15 cancer types. Because this analysis shows association rather than direction, both RRAS-to-partner and partner-to-RRAS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RRAS versus CAVIN1 in LUNG_NSCLC_LUSC, with a Pearson correlation of 0.81.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RRAS→partner) and Y-score (partner→RRAS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	CAVIN1 →	+6.275	+3.779	<.001	<.001	3	16
BONE	OPTN →	+2.365	+1.615	<.001	<.001	3	16
LIVER	FAM214B →	+2.512	+2.962	<.001	<.001	3	15
LUNG_NSCLC_LUSC	CD151 →	+1.969	+2.788	<.001	.001	3	14
LUNG_SCLC	PLIN3 →	+2.805	+2.546	<.001	<.001	3	14
LIVER	PPP1R18 →	+2.306	+2.160	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,436 associations by consensus.

RRAS vs CAVIN1 — LUNG_NSCLC_LUSC

Explore this scatter interactively →