RRAS

Across TCGA cell cohorts, RRAS RNA expression is significantly associated with the go_rna of many other GO terms, with 6,234 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible RRAS-associated GO terms across cancer lineages are Positive regulation of cell-matrix adhesion, Skeletal myofibril assembly, and Carbohydrate derivative catabolic process. Each is linked with RRAS in more than 16 cancer types. Because this analysis shows association rather than direction, both RRAS-to-partner and partner-to-RRAS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell-matrix adhesion grouped by RRAS-low versus RRAS-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RRAS→partner) and Y-score (partner→RRAS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of cell-matrix adhesion →	+0.156	+1.437	<.001	<.001	3	17
LUNG_SCLC	Skeletal myofibril assembly →	+0.808	+2.166	.003	.004	3	16
BONE	Carbohydrate derivative catabolic process →	+0.084	+1.634	.002	.002	3	16
LUNG_SCLC	Negative regulation of immune effector process →	+0.206	+2.620	<.001	<.001	3	16
STOMACH	Regulation of proteolysis →	+0.123	+1.983	<.001	<.001	3	16
BONE	Membrane raft organization →	+0.202	+1.726	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,234 associations by consensus.

Positive regulation of cell-matrix adhesion by RRAS expression — BONE

Explore this box plot interactively →