RRAGC

Across TCGA patient cohorts, RRAGC RNA expression is significantly associated with the mutation status of many other genes, with 10,026 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RRAGC-associated genes across cancer lineages are TP53, VPS13C, and COL6A3. Each is linked with RRAGC in more than 10 cancer types. Because this analysis shows association rather than direction, both RRAGC-to-partner and partner-to-RRAGC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TP53 grouped by RRAGC-low versus RRAGC-high in PRAD.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RRAGC→partner) and Y-score (partner→RRAGC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PRAD	TP53 →	+2.866	+0.288	<.001	<.001	3	11
SKCM	VPS13C →	+1.845	+0.392	.002	<.001	3	4
UCEC	COL6A3 →	+1.389	+0.272	<.001	<.001	3	4
UCEC	PKHD1 →	+1.464	+0.233	<.001	.002	3	4
UCEC	CASR →	+1.678	+0.360	<.001	<.001	3	4
UCEC	PTPRU →	+2.479	+0.425	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,026 associations by consensus.

TP53 by RRAGC expression — PRAD

Explore this box plot interactively →