RPUSD4

Across TCGA patient cohorts, RPUSD4 protein abundance is significantly associated with the RNA expression of many other genes, with 9,886 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RPUSD4-associated genes across cancer lineages are LINC00607, ARHGAP22, and EI24. Each is linked with RPUSD4 in more than 4 cancer types. Because this analysis shows association rather than direction, both RPUSD4-to-partner and partner-to-RPUSD4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPUSD4 versus LINC00607 in BRCA, with a Pearson correlation of -0.22.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPUSD4→partner) and Y-score (partner→RPUSD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LINC00607 →	-0.541	-0.315	.003	.005	3	5
HNSC	ARHGAP22 →	-0.524	-0.269	<.001	<.001	3	4
OV	EI24 →	+0.482	+0.422	.008	.006	3	4
BRCA	SLC45A1 →	-0.837	-0.405	<.001	<.001	3	4
UCEC	HSPD1 →	+0.800	+0.308	.004	<.001	3	4
BRCA	PPM1M →	-0.506	-0.383	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,886 associations by consensus.

RPUSD4 vs LINC00607 — BRCA

Explore this scatter interactively →