RPUSD4

Across TCGA cell cohorts, RPUSD4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,068 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RPUSD4-associated GO terms across cancer lineages are Mitochondrial tRNA pseudouridine synthesis, rRNA pseudouridine synthesis, and Platelet activating factor catabolic process. Each is linked with RPUSD4 in more than 19 cancer types. Because this analysis shows association rather than direction, both RPUSD4-to-partner and partner-to-RPUSD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial tRNA pseudouridine synthesis grouped by RPUSD4-low versus RPUSD4-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPUSD4→partner) and Y-score (partner→RPUSD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Mitochondrial tRNA pseudouridine synthesis →	+0.196	+1.161	<.001	.002	3	20
BONE	rRNA pseudouridine synthesis →	+0.172	+0.981	<.001	<.001	3	18
OVARY	Platelet activating factor catabolic process →	+0.200	+0.863	<.001	<.001	3	16
BONE	Meiotic chromosome condensation →	+0.176	+0.722	<.001	<.001	3	16
OVARY	Ether catabolic process →	+0.200	+0.863	<.001	<.001	3	16
OESOPHAGUS	tRNA pseudouridine synthesis →	+0.123	+0.783	.002	.002	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,068 associations by consensus.

Mitochondrial tRNA pseudouridine synthesis by RPUSD4 expression — URINARY_TRACT

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