RPUSD4

Across TCGA cell cohorts, RPUSD4 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RPUSD4-associated genes across cancer lineages are MYF5, MYOD1, and CRYGC. Each is linked with RPUSD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPUSD4-to-partner and partner-to-RPUSD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYF5 grouped by RPUSD4-low versus RPUSD4-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPUSD4→partner) and Y-score (partner→RPUSD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MYF5 →	+0.013	+5.201	<.001	.006	3	1
BLOOD_Leukemia	MYOD1 →	+0.015	+4.922	.001	.009	3	1
BLOOD_Leukemia	CRYGC →	+0.035	+5.969	<.001	.001	3	1
BLOOD_Leukemia	MC2R →	+0.006	+5.969	<.001	.001	3	1
BLOOD_Leukemia	USP17L3 →	+0.012	+4.922	.009	.009	3	1
BLOOD_Leukemia	STMND1 →	+0.974	+5.201	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

MYF5 by RPUSD4 expression — BLOOD_Leukemia

Explore this box plot interactively →