RPSA

Across TCGA patient cohorts, RPSA protein abundance is significantly associated with the RNA expression of many other genes, with 14,903 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RPSA-associated genes across cancer lineages are KIAA1109, TAPT1, and PPM1A. Each is linked with RPSA in more than 5 cancer types. Because this analysis shows association rather than direction, both RPSA-to-partner and partner-to-RPSA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPSA versus KIAA1109 in BRCA, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPSA→partner) and Y-score (partner→RPSA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KIAA1109 →	-0.706	-0.207	<.001	<.001	3	6
BRCA	TAPT1 →	-0.730	-0.175	<.001	<.001	3	6
BRCA	PPM1A →	-0.584	-0.302	<.001	<.001	3	5
BRCA	PLSCR4 →	-0.863	-0.176	<.001	<.001	3	5
BRCA	LCA5 →	-0.739	-0.217	<.001	.003	3	5
BRCA	SECISBP2L →	-0.638	-0.179	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,903 associations by consensus.

RPSA vs KIAA1109 — BRCA

Explore this scatter interactively →