RPS5

Across TCGA patient cohorts, RPS5 protein abundance is significantly associated with the RNA expression of many other genes, with 14,475 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible RPS5-associated genes across cancer lineages are SHE, KLHDC1, and FHL5. Each is linked with RPS5 in more than 8 cancer types. Because this analysis shows association rather than direction, both RPS5-to-partner and partner-to-RPS5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPS5 versus SHE in CCRCC, with a Pearson correlation of -0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS5→partner) and Y-score (partner→RPS5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SHE →	-0.640	-0.153	<.001	<.001	3	9
BRCA	KLHDC1 →	-0.686	-0.181	<.001	.006	3	8
PDAC	FHL5 →	-1.026	-0.196	<.001	<.001	3	7
CCRCC	TEK →	-0.696	-0.136	<.001	<.001	3	7
CCRCC	TMEM204 →	-1.167	-0.161	<.001	.004	3	7
HNSC	RGL1 →	-0.693	-0.120	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,475 associations by consensus.

RPS5 vs SHE — CCRCC

Explore this scatter interactively →