RPS5

Across TCGA cell cohorts, RPS5 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RPS5-associated genes across cancer lineages are TEX55, MRGPRD, and OR11H6. Each is linked with RPS5 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPS5-to-partner and partner-to-RPS5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TEX55 grouped by RPS5-low versus RPS5-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS5→partner) and Y-score (partner→RPS5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	TEX55 →	+0.037	+4.321	<.001	.009	3	1
CNS	MRGPRD →	+0.563	+4.169	<.001	.008	3	1
CNS	OR11H6 →	+0.016	+4.321	.001	.009	3	1
CNS	FGF3 →	+0.039	+5.566	<.001	<.001	3	1
LARGE_INTESTINE	ZNF831 →	+0.018	+4.273	<.001	.006	3	1
LARGE_INTESTINE	OR14K1 →	+0.102	+5.022	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

TEX55 by RPS5 expression — CNS

Explore this box plot interactively →