RPRM

Across TCGA cell cohorts, RPRM RNA expression is significantly associated with the go_rna of many other GO terms, with 1,405 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible RPRM-associated GO terms across cancer lineages are Regulation of syncytium formation by plasma membrane fusion, Regulation of myoblast fusion, and Cartilage development. Each is linked with RPRM in more than 7 cancer types. Because this analysis shows association rather than direction, both RPRM-to-partner and partner-to-RPRM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of syncytium formation by plasma membrane fusion grouped by RPRM-low versus RPRM-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPRM→partner) and Y-score (partner→RPRM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of syncytium formation by plasma membrane fusion →	+0.074	+2.017	.005	.002	3	8
LUNG_SCLC	Regulation of myoblast fusion →	+0.058	+1.710	.003	.001	3	6
LUNG_SCLC	Cartilage development →	-0.081	-2.162	<.001	.002	3	6
OESOPHAGUS	Negative regulation of DNA-templated transcription, elongation →	+0.110	+0.756	<.001	<.001	3	6
LARGE_INTESTINE	Negative regulation of peptidase activity →	-0.145	-0.544	<.001	.003	3	5
LUNG_SCLC	NADH dehydrogenase complex assembly →	+0.114	+2.393	.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,405 associations by consensus.

Regulation of syncytium formation by plasma membrane fusion by RPRM expression — LUNG_SCLC

Explore this box plot interactively →