RPP38-DT

Across TCGA patient cohorts, RPP38-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 7,605 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RPP38-DT-associated proteins across cancer lineages are SPAG1_S418, NUP153, and TNKS1BP1_S1073. Each is linked with RPP38-DT in more than 3 cancer types. Because this analysis shows association rather than direction, both RPP38-DT-to-partner and partner-to-RPP38-DT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPP38-DT versus SPAG1_S418 in UCEC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RPP38-DT→partner) and Y-score (partner→RPP38-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SPAG1_S418 →	+1.206	+0.780	<.001	<.001	3	4
BRCA	NUP153 →	+0.284	+0.309	<.001	<.001	3	3
HNSC	TNKS1BP1_S1073 →	-0.354	-0.378	.001	.009	3	3
GBM	PTBP2 →	+0.579	+0.219	<.001	.005	3	3
LSCC	CDH11 →	-0.532	-0.322	<.001	<.001	3	3
GBM	PARD3_S873 →	+0.623	+0.328	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,605 associations by consensus.

RPP38-DT vs SPAG1_S418 — UCEC

Explore this scatter interactively →