RPP38-DT

Across TCGA pan-cancer cohorts, RPP38-DT RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated RPP38-DT data layer.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher RPP38-DT RNA is associated with better overall survival. In most high-consensus cancer types, elevated RPP38-DT expression acts as an unfavorable survival marker, although some lineages such as PAAD and LUAD show a favorable association.

PAAD, ACC, and LUAD are the cancer types where RPP38-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	OS	Median	All	0.627	0.364	<.001	78	view →
ACC	DFS	Tertile	All	0.361	0.824	<.001	62	view →
LUAD	OS	Tertile	II,III,IV	0.779	0.551	.003	55	view →
KIRC	DFS	Median	All	0.765	0.838	.007	40	view →
UCEC	DFS	Tertile	II,III,IV	0.660	0.810	.011	40	view →
HNSC	DFS	Quartile	IV	0.519	0.242	.002	37	view →
UCS	DFS	Quartile	III,IV	0.574	0.193	.015	30	view →
DLBC	DFS	Median	III,IV	0.074	0.984	.003	25	view →
KIRP	OS	Quartile	II,III,IV	0.107	0.718	<.001	18	view →
LIHC	DFS	Median	All	0.365	0.497	.004	16	view →
OV	DFS	Median	IV	0.565	0.356	.007	12	view →
SCLC	DFS	Median	II,III,IV	0.776	0.247	.011	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

RPP38-DT–PAAD (OS)

Open the PAAD breakdown →