RPLP1

Across TCGA patient cohorts, RPLP1 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPLP1-associated genes across cancer lineages are MEMO1P5, MIR3691, and RNU6-771P. Each is linked with RPLP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPLP1-to-partner and partner-to-RPLP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEMO1P5 grouped by RPLP1-low versus RPLP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPLP1→partner) and Y-score (partner→RPLP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEMO1P5 →	+0.178	+6.027	.007	.002	3	1
UCEC	MIR3691 →	+0.816	+5.694	<.001	.003	3	1
LUAD	RNU6-771P →	+0.228	+7.930	<.001	.008	3	1
LUAD	RN7SKP142 →	+0.083	+7.930	<.001	.008	3	1
LUAD	TTTY23 →	+0.154	+7.930	<.001	.008	3	1
LUAD	RN7SKP46 →	+0.114	+7.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

MEMO1P5 by RPLP1 expression — UCEC

Explore this box plot interactively →