RPLP1

Across TCGA pan-cancer cohorts, RPLP1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of RPLP1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPLP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPLP1 is over-expressed in tumor, although a few such as UCEC and KICH show the opposite, repressed pattern.

KIRC, LIHC, and KIRP are the cancer types where RPLP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPLP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	IV	+0.907	<.001	12	view →
LIHC	Female	II,III,IV	+1.345	<.001	9	view →
KIRP	All	II,III,IV	+0.608	.001	8	view →
COAD	Female	II,III,IV	+1.070	<.001	6	view →
LUSC	Male	All	+0.611	<.001	6	view →
CHOL	Male	All	+1.893	<.001	3	view →
UCEC	All	II,III,IV	−0.578	.037	2	view →
KICH	Female	All	−0.525	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

RPLP1–KIRC

Open the KIRC breakdown →