RPL36AP40

Across TCGA pan-cancer cohorts, RPL36AP40 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated RPL36AP40 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher RPL36AP40 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPL36AP40 expression acts as an unfavorable survival marker, although some lineages such as CESC and MESO show a favorable association.

KIRP, UCEC, and CHOL are the cancer types where RPL36AP40 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Tertile	All	0.421	0.785	<.001	83	view →
UCEC	DFS	Tertile	All	0.846	0.912	.002	72	view →
CHOL	DFS	Tertile	All	0.089	0.470	.004	45	view →
CESC	DFS	Tertile	II,III,IV	0.789	0.355	.006	38	view →
MESO	OS	Tertile	All	0.662	0.468	.005	35	view →
SKCM	OS	Median	All	0.827	0.916	.005	29	view →
READ	DFS	Tertile	IV	0.095	0.697	.014	21	view →
COAD	OS	Tertile	IV	0.252	0.596	.008	18	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
DLBC	OS	Median	All	1.000	0.482	.011	17	view →
LUSC	OS	Quartile	II,III,IV	0.612	0.832	.010	14	view →
LGG	OS	Tertile	All	0.906	0.773	.026	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

RPL36AP40–KIRP (OS)

Open the KIRP breakdown →